A massive gene hunt reveals how brain cells are made

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this process possible. Among the discoveries is PEDS1, a gene now linked to a previously unknown neurodevelopmental disorder in children. When PEDS1 does not work properly, brain growth and nerve cell formation are impaired. The findings help explain how early genetic changes can shape brain development and disease.

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